Annual report pursuant to Section 13 and 15(d)

Property and Equipment - Components of Property and Equipment (Detail)

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Property and Equipment - Components of Property and Equipment (Detail) - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Property Plant And Equipment [Line Items]    
Total property and equipment, Gross $ 2,163 $ 2,949
Less: Accumulated depreciation and amortization (2,054) (2,616)
Total property and equipment, net 109 333
Computer and Office Equipment    
Property Plant And Equipment [Line Items]    
Total property and equipment, Gross 532 532
Laboratory Equipment    
Property Plant And Equipment [Line Items]    
Total property and equipment, Gross 1,108 1,894
Leasehold Improvements    
Property Plant And Equipment [Line Items]    
Total property and equipment, Gross $ 523 $ 523