Annual report pursuant to Section 13 and 15(d)

Income Taxes - Additional Information (Detail)

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Income Taxes - Additional Information (Detail) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Income Taxes Disclosure [Line Items]      
Income tax (benefit) provision $ 0 $ 0 $ (202,000)
NOL DTA related to excess benefits from stock option exercises 500,000    
Increase (decrease) in valuation allowance 9,000,000 (6,200,000) $ 7,800,000
Accrued interest or penalties 0 $ 0  
Federal      
Income Taxes Disclosure [Line Items]      
Net operating loss carryforwards $ 143,000,000    
Year net operating loss carryforwards begin to expire 2021    
Research and development credits $ 10,500,000    
Year research and development credits begin to expire 2022    
State      
Income Taxes Disclosure [Line Items]      
Net operating loss carryforwards $ 94,000,000    
Year net operating loss carryforwards begin to expire 2017    
Research and development credits $ 5,900,000