Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies - Additional Information (Detail)

v3.7.0.1
Commitments and Contingencies - Additional Information (Detail)
 12 Months Ended
Dec. 31, 2016
USD ($)
ft²
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Other Commitments [Line Items]      
Rent expense $ 700,000 $ 700,000 $ 800,000
Purchase commitments $ 300,000    
Non-cancelable Facility Sublease beginning October 1, 2011      
Other Commitments [Line Items]      
Square feet of laboratory space and office space | ft² 31,104    
Lease agreement expiration date Apr. 30, 2017    
Aggregate rent over life of lease $ 3,400,000    
Security deposit for lease $ 60,000    
Non-cancelable Facility Sublease beginning December 1, 2013      
Other Commitments [Line Items]      
Square feet of laboratory space and office space | ft² 7,934    
Lease agreement expiration date Dec. 31, 2016    
Aggregate rent over life of lease $ 700,000    
Lease termination date for office space 2015-06