Annual report pursuant to Section 13 and 15(d)

Research and Development Agreements - Schedule of Research and Development Revenue from Related Party Relates to Revenue from Research and Development Agreements (Detail)

v3.23.1
Research and Development Agreements - Schedule of Research and Development Revenue from Related Party Relates to Revenue from Research and Development Agreements (Detail) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2022
Dec. 31, 2021
Revenue Recognition [Line Items]      
Research and development revenue recognized $ 2,600 $ 19,754 $ 38,697
Millennium Pharmaceuticals, Inc.      
Revenue Recognition [Line Items]      
Research and development revenue recognized   2,586 13,136
Millennium Pharmaceuticals, Inc. | Takeda Development Agreement      
Revenue Recognition [Line Items]      
Research and development revenue recognized   0 13,114
Millennium Pharmaceuticals, Inc. | Takeda Multi Target Agreement      
Revenue Recognition [Line Items]      
Research and development revenue recognized   $ 2,586 $ 22