Annual report pursuant to Section 13 and 15(d)

Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2022
Dec. 31, 2021
Revenue Recognition [Line Items]      
Total research and development revenue $ 2,600 $ 19,754 $ 38,697
JAPAN      
Revenue Recognition [Line Items]      
Total research and development revenue   2,586 13,136
UNITED STATES      
Revenue Recognition [Line Items]      
Total research and development revenue   $ 17,168 $ 25,561