Annual report pursuant to Section 13 and 15(d)

Income Taxes - Schedule of Reconciliation of Income Taxes at Statutory Federal Income Tax Rate to Net Income Taxes (Detail)

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Income Taxes - Schedule of Reconciliation of Income Taxes at Statutory Federal Income Tax Rate to Net Income Taxes (Detail) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
U.S. federal taxes (benefit) at statutory rate $ (17,431,000) $ (22,032,000)
State federal income tax benefit (3,834,000) (895,000)
Permanent differences 15,000 (46,000)
Stock compensation 1,666,000 524,000
Research and development credits (2,840,000) (4,043,000)
Change in valuation allowance due to operations 24,219,000 26,484,000
Change in state rate and carryovers (1,795,000) 13,000
Total $ 0 $ 5,000.0