Annual report pursuant to Section 13 and 15(d)

Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Revenue Recognition [Line Items]    
Total research and development revenue $ 38,697 $ 15,635
JAPAN    
Revenue Recognition [Line Items]    
Total research and development revenue 13,136 6,567
UNITED STATES    
Revenue Recognition [Line Items]    
Total research and development revenue $ 25,561 $ 9,068