Annual report pursuant to Section 13 and 15(d)

Property and Equipment - Components of Property and Equipment (Detail)

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Property and Equipment - Components of Property and Equipment (Detail) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2012
Dec. 31, 2011
Property, Plant and Equipment [Line Items]    
Total property and equipment, Gross $ 2,552 $ 2,293
Less: Accumulated depreciation and amortization (1,740) (1,750)
Total property and equipment, net 812 543
Computer and office equipment [Member]
   
Property, Plant and Equipment [Line Items]    
Total property and equipment, Gross 436 337
Laboratory equipment [Member]
   
Property, Plant and Equipment [Line Items]    
Total property and equipment, Gross 1,593 1,316
Leasehold improvements [Member]
   
Property, Plant and Equipment [Line Items]    
Total property and equipment, Gross $ 523 $ 640