Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS

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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (USD $)
In Thousands, except Per Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Revenue $ 5,867 $ 62   
Operating expenses:      
Research and development 18,786 24,388 18,937
General and administrative 7,080 5,710 4,971
Total operating expenses 25,866 30,098 23,908
Loss from operations (19,999) (30,036) (23,908)
Interest income (expense), net 80 25 60
Other income (expense), net (51,216) 4,358 5,166
Net loss (71,135) (25,653) (18,682)
Other comprehensive income (loss):      
Unrealized gain (loss) on available for sale securities 12 (2) 25
Comprehensive loss $ (71,123) $ (25,655) $ (18,657)
Net loss per common share:      
Basic $ (1.31) $ (0.56) $ (0.56)
Diluted $ (1.31) $ (0.56) $ (0.56)
Weighted average number of shares used in per common share calculations:      
Basic 54,219 45,900 33,654
Diluted 54,219 45,900 33,654