Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Impact of Adoption on Condensed Consolidated Statement of Cash Flows (Detail)

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Research and Development Agreements - Schedule of Impact of Adoption on Condensed Consolidated Statement of Cash Flows (Detail) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Revenue Recognition [Line Items]        
Net loss $ 9,695 $ 4,064 $ 18,409 $ 5,258
Changes in operating assets and liabilities:        
Other current assets     (120) 0
Net cash used in operating activities     (14,136) $ (2,290)
ASC 2014-09 | Effect of Adoption of ASC 606        
Revenue Recognition [Line Items]        
Net loss 11   79  
Changes in operating assets and liabilities:        
Other current assets     (79)  
Net cash used in operating activities     0  
ASC 2014-09 | Balance without Adoption of ASC 606        
Revenue Recognition [Line Items]        
Net loss $ 9,706   18,488  
Changes in operating assets and liabilities:        
Other current assets     (41)  
Net cash used in operating activities     $ (14,136)