Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Contract Assets and Contract Liabilities for Performance Obligations related to Collaboration Agreements (Parenthetical) (Detail)

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Research and Development Agreements - Schedule of Contract Assets and Contract Liabilities for Performance Obligations related to Collaboration Agreements (Parenthetical) (Detail) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Contract With Customer Asset And Liability [Line Items]        
Research and development revenue $ 944,000 $ 0 $ 1,175,000 $ 1,760,000
Deferred Revenue        
Contract With Customer Asset And Liability [Line Items]        
Research and development revenue     $ 432,000