Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) (Parenthetical)

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Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) (Parenthetical) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Statement Of Stockholders Equity [Abstract]    
Issuance of common stock in a public offering and to Takeda and certain other investors, issuance costs $ 3.8 $ 2.4