Annual report pursuant to Section 13 and 15(d)

Equity Incentive Plans and Stock Based Compensation - Stock-Based Compensation Expense (Detail)

v2.4.0.8
Equity Incentive Plans and Stock Based Compensation - Stock-Based Compensation Expense (Detail) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense $ 4,922 $ 3,010 $ 1,039
Research and Development [Member]
     
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense 2,562 1,521 471
General and Administrative [Member]
     
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense $ 2,360 $ 1,489 $ 568