Quarterly report pursuant to Section 13 or 15(d)

Collaboration Arrangements - Additional Information (Detail)

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Collaboration Arrangements - Additional Information (Detail) (USD $)
In Millions, unless otherwise specified
 3 Months Ended 6 Months Ended 9 Months Ended 10 Months Ended 9 Months Ended
Sep. 30, 2012
Mar. 31, 2012
Jun. 30, 2012
Sep. 30, 2012
Oct. 31, 2012
Subsequent Event [Member]
Sep. 30, 2012
Development And Regulatory [Member]
Sep. 30, 2012
Commercialization Milestones [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]              
Company received an upfront payment   $ 25          
Milestone payments received     20        
Milestone payments expected in fourth quarter of 2012         22.5    
Potential future milestones, related to development and regulatory           142.5 340.0
Additional potential milestone payments achievable in the near term         42.5    
Percentage of payment to be made for worldwide development expenses       70.00%      
Portion of profits that Company is eligible to participate in United States, depending upon total sales       50.00%      
Company recognized of revenue 1.8     3.8      
Company earned a reimbursement for eligible worldwide development expenses $ 5.0     $ 10.0