Quarterly report pursuant to Section 13 or 15(d)

Collaboration Arrangements - Additional Information (Detail)

v2.4.0.8
Collaboration Arrangements - Additional Information (Detail) (USD $)
In Millions, unless otherwise specified
3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 32 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Mar. 31, 2014
Merck KGaA
Sep. 30, 2014
Merck KGaA
Sep. 30, 2014
Merck KGaA
Sep. 30, 2014
Merck KGaA
United States
Sep. 30, 2014
Merck KGaA
Regulatory and Development Milestones
Sep. 30, 2014
Merck KGaA
Commercialization Milestones
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Upfront and milestone payments received to date         $ 12.5   $ 110.0      
Potential future milestones                 100 340
Merck KGaA's percentage share of worldwide development expenses           70.00%        
Portion of profits that Company is eligible to participate, depending upon total sales               50.00%    
Revenue recognized by the Company 3.7 3.2 11.0 9.3            
Company earned a reimbursement for eligible worldwide development expenses $ 4.8 $ 5.5 $ 14.2 $ 11.6