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Collaboration Arrangements - Additional Information (Detail) (USD $)
In Millions, unless otherwise specified |
3 Months Ended | 6 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended | 14 Months Ended | 6 Months Ended | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Jun. 30, 2013
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Jun. 30, 2012
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Jun. 30, 2013
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Jun. 30, 2012
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Mar. 31, 2013
Agreements with Merck KGaA [Member]
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Jun. 30, 2013
Agreements with Merck KGaA [Member]
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Jun. 30, 2012
Agreements with Merck KGaA [Member]
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Dec. 31, 2012
Agreements with Merck KGaA [Member]
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Mar. 31, 2013
Agreements with Merck KGaA [Member]
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Jun. 30, 2013
Agreements with Merck KGaA [Member]
Regulatory and development milestones [Member]
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Jun. 30, 2013
Agreements with Merck KGaA [Member]
Regulatory and development milestones [Member]
2013 Potential Milestone payments [Member]
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Jun. 30, 2013
Agreements with Merck KGaA [Member]
Commercialization milestones [Member]
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| Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] | ||||||||||||
| Upfront payment received | $ 25 | |||||||||||
| Milestone payments received to date | 42.5 | 72.5 | ||||||||||
| Potential future milestones | 112.5 | 12.5 | 340.0 | |||||||||
| Merck's percentage share of worldwide development expenses | 70.00% | 70.00% | 70.00% | |||||||||
| Portion of profits that Company is eligible to participate in United States, depending upon total sales | 50.00% | 50.00% | 50.00% | |||||||||
| Revenue recognized by the Company | 3.2 | 1.8 | 6.1 | 2.0 | ||||||||
| Collaboration payments achieved and received | 30.0 | 97.5 | ||||||||||
| Company earned a reimbursement for eligible worldwide development expenses | $ 2.5 | $ 3.9 | $ 6.1 | $ 5.0 | ||||||||