Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Impact of Adoption on Condensed Consolidated Statement of Cash Flows (Detail)

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Research and Development Agreements - Schedule of Impact of Adoption on Condensed Consolidated Statement of Cash Flows (Detail) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Revenue Recognition [Line Items]    
Net loss $ 8,714 $ 1,195
Changes in operating assets and liabilities:    
Other current assets (71) 0
Net cash used in operating activities (8,983) $ (2,654)
ASC 2014-09 | Effect of Adoption of ASC 606    
Revenue Recognition [Line Items]    
Net loss 68  
Changes in operating assets and liabilities:    
Other current assets (68)  
Net cash used in operating activities 0  
ASC 2014-09 | Balance without Adoption of ASC 606    
Revenue Recognition [Line Items]    
Net loss 8,782  
Changes in operating assets and liabilities:    
Other current assets (3)  
Net cash used in operating activities $ (8,983)