Quarterly report pursuant to Section 13 or 15(d)

Stock Based Compensation - Stock-Based Compensation Expense (Detail)

v3.5.0.2
Stock Based Compensation - Stock-Based Compensation Expense (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock-based compensation expense $ 792 $ 1,476 $ 2,437 $ 4,792
Research and Development        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock-based compensation expense 426 846 1,050 2,837
General and Administrative        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock-based compensation expense $ 366 $ 630 $ 1,387 $ 1,955