Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit)

v3.8.0.1
Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($)
Total
Convertible Preferred Stock
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Balances, value at Dec. 31, 2015 $ (27,317,000)   $ 0 $ 456,000 $ 0 $ (27,773,000)
Temporary equity, Balances, shares at Dec. 31, 2015   9,116,405        
Temporary equity, Balances, value at Dec. 31, 2015   $ 24,299,000        
Balances, shares at Dec. 31, 2015     213,128      
Issuance of common stock pursuant to stock plans, value 3,000 0 $ 0 3,000 0 0
Issuance of common stock pursuant to stock plans, shares     1,513      
Stock-based compensation 109,000 0 $ 0 109,000 0 0
Stock-based compensation, shares     0      
Deemed dividends on preferred stock (1,572,000) 0 $ 0 0 0 (1,572,000)
Temporary equity, Deemed dividends on preferred stock 1,572,000 1,572,000        
Unrealized gain (loss) on available-for-sale securities 0 0 0 0 0 0
Net income (loss) (11,028,000) $ 0 0 0 0 (11,028,000)
Balances, value at Dec. 31, 2016 (39,805,000)   $ 0 568,000 0 (40,373,000)
Temporary equity, Balances, shares at Dec. 31, 2016   9,116,405        
Temporary equity, Balances, value at Dec. 31, 2016 $ 25,871,000 $ 25,871,000        
Balances, shares at Dec. 31, 2016 214,641   214,641      
Issuance of common stock pursuant to stock plans, value $ 61,000 $ 0 $ 0 61,000 0 0
Issuance of common stock pursuant to stock plans, shares     17,430      
Conversion of preferred stock to common stock in connection with merger 26,829,000   $ 9,000 26,820,000 0 0
Temporary equity, Amount of shares of preferred stock outstanding that were converted to common stock in connection with merger   (9,116,405)        
Temporary equity, Conversion of preferred stock to common stock in connection with merger (26,829,000) $ (26,829,000)        
Conversion of preferred stock to common stock in connection with merger, shares     9,220,478      
Conversion of preferred stock warrants to common stock in connection with merger 87,000 0 $ 0 87,000 0 0
Conversion of preferred stock warrants to common stock in connection with merger, shares     12,653      
Conversion of redeemable convertible notes to common stock 15,105,000 0 $ 2,000 15,103,000 0 0
Conversion of redeemable convertible notes to common stock, shares     2,208,716      
Issuance of common stock and assumption of options in connection with the merger 39,670,000 0 $ 7,000 39,663,000 0 0
Issuance of common stock and assumption of options in connection with the merger, shares     6,508,356      
Issuance of common stock to Takeda and certain other investors, net of issuance costs of $2.4 million 57,648,000 0 $ 9,000 57,639,000 0 0
Issuance of common stock to Takeda and certain other investors, net of issuance costs of $2.4 million, shares     8,716,056      
Stock-based compensation 1,792,000 0 $ 0 1,792,000 0 0
Stock-based compensation, shares     0      
Deemed dividends on preferred stock (958,000) 0 $ 0 0 0 (958,000)
Temporary equity, Deemed dividends on preferred stock 958,000 958,000        
Net income (loss) (23,140,000) $ 0 0 0 0 (23,140,000)
Balances, value at Dec. 31, 2017 77,289,000   $ 27,000 $ 141,733,000 $ 0 $ (64,471,000)
Temporary equity, Balances, shares at Dec. 31, 2017   0        
Temporary equity, Balances, value at Dec. 31, 2017 $ 0 $ 0        
Balances, shares at Dec. 31, 2017 26,898,330   26,898,330