Annual report pursuant to Section 13 and 15(d)

Organization and Summary of Significant Accounting Policies - Additional Information (Detail)

v3.20.4
Organization and Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
USD ($)
Segment
Dec. 31, 2019
USD ($)
Jan. 01, 2019
USD ($)
Organization And Summary Of Significant Accounting Policies [Line Items]      
Deferred revenue, current, related party $ 789 $ 8,780  
Reclassification from deferred revenue, non-current to deferred revenue, non-current, related party   400  
Reclassification from deferred revenue to deferred revenue, related party   19,700  
Right-of-use asset 11,104 9,959 $ 4,180
Lease liabilities $ 14,423    
Reportable segment | Segment 1    
ASU 2016-02      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Right-of-use asset     4,180
Lease liabilities     $ 4,700
Patents      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Amortization expense $ 100 100  
Estimated expense, next twelve months 100    
Estimated expense, year two 100    
Estimated expense, year three 100    
Estimated expense, year four $ 100    
In-process Research and Development      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Impairment of long lived assets   $ 22,100  
Minimum      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Lessee, operating leases remaining lease term. 2 years    
Lessee, finance leases remaining lease term. 1 year    
Lessee, operating leases renewal lease term 3 years    
Maximum      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Lessee, operating leases remaining lease term. 8 years    
Lessee, operating leases renewal lease term 5 years    
Leasehold Improvements | Minimum      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Property and equipment, estimated useful lives 3 years    
Leasehold Improvements | Maximum      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Property and equipment, estimated useful lives 7 years    
Revenue | Credit Risk | Takeda      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Percentage of total revenues 35.00% 88.00%  
Revenue | Credit Risk | Vertex Pharmaceuticals Inc      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Percentage of total revenues 48.00% 0.00%  
Other Assets      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Restricted cash $ 3,700 $ 3,000  
Gross value of patents $ 1,200 $ 1,300