FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
ANDERSON DAVID L
  2. Issuer Name and Ticker or Trading Symbol
THRESHOLD PHARMACEUTICALS INC [THLD]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
755 PAGE MILL ROAD, SUITE A-200
3. Date of Earliest Transaction (Month/Day/Year)
10/05/2009
(Street)

PALO ALTO, CA 94304-1005
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 10/05/2009   P(1)   13,779 A $ 1.91 (2) 17,945 I By Ltd Partnership (3)
Common Stock 10/05/2009   P(1)   13,779 A $ 1.91 (2) 64,199 I By Profit Sharing Plan Trust (4)
Common Stock               6,837 I By Trust (5)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Common Stock Warrant $ 2.23 10/05/2009   P(1)   5,511   10/05/2009 10/05/2014 Common Stock 5,511 $ 1.91 (2) 5,511 I By Ltd Partnership (3)
Common Stock Warrant $ 2.23 10/05/2009   P(1)   5,511   10/05/2009 10/05/2014 Common Stock 5,511 $ 1.91 (2) 5,511 I By Profit Sharing Plan Trust (4)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
ANDERSON DAVID L
755 PAGE MILL ROAD, SUITE A-200
PALO ALTO, CA 94304-1005
    X    

Signatures

 Robert Yin, by power of attorney   10/07/2009
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Acquired from the issuer pursuant to a Securities Purchase Agreement dated September 29, 2009, with a closing date of October 5, 2009.
(2) Purchase price per unit. Each unit consists of 1 common share and a warrant to purchase 0.4 of a share of common stock at an exercise price of $2.23 per share.
(3) Shares held by a limited partnership of which the reporting person is the General Partner. The reporting person disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest therein.
(4) Shares held by SHV Profit Sharing Plan, a retirement trust, for the benefit of the reporting person.
(5) Shares held by a trust of which the reporting person is the trustee. The reporting person disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest therein.
 
Remarks:
This Form 4 excludes certain shares held by Sutter Hill Ventures, A California Limited Partnership which are reported separately on Form 4 dated October 5, 2009.  The reporting person is a Managing Director of the General Partner of this partnership and disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest therein.
This Form 4 also excludes certain shares held by Sutter Hill Entrepreneurs Fund (AI), LP and Sutter Hill Entrepreneurs Fund (QP), LP which have previously been reported here. In the future, when there are activities in these partnerships, these certain shares will also be reported separately.  The reporting person is a Managing Director of the General Partner of these partnerships and disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest therein.

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