Exhibit 24


STATEMENT APPOINTING DESIGNATED FILER AND AUTHORIZED SIGNATORIES
                       SEPTEMBER 3, 2002


     Each of the entities listed on Schedule A attached hereto (each, a
"Reporting Entity") and each party listed on Schedule B attached hereto
(each, a "Reporting Individual"; together with the Reporting Entities,
the "Reporting Persons") hereby authorizes and designates Chris Adams
and Barclay Nicholson (each, a "Designated Filer"), for so long as they
are employed by Three Arch Partners, to prepare and file on behalf of
such Reporting Persons, individually or jointly together with other
Reporting Persons, any and all reports, notices, communications and other
documents (including, but not limited to, reports on Schedule 13D,
Schedule 13G, Form 3, Form 4 and Form 5) (the "Reports") that such
Reporting Person may be required to file with the United States Securities
and Exchange Commission or with any regulatory body, including United States
federal, state and self-regulatory bodies, with respect to the Reporting
Person's ownership of, or transactions in, the securities of any entity
whose securities are beneficially owned (directly or indirectly) by such
Reporting Person (collectively, the "Companies").

     Each Reporting Person hereby further authorizes and designates Chris
Adams and Barclay Nicholson (each, an "Authorized Signatory") to execute
and file on behalf of such Reporting Person the Reports and to perform any
and all other acts, which in the opinion of the Designated Filer or
Authorized Signatory may be necessary or incidental to the performance of
the foregoing powers herein granted.

     The authority of each Designated Filer and each Authorized Signatory
under this document with respect to each Reporting Person shall continue
until such Reporting Person is no longer required to file any Reports with
respect to the Reporting Person's ownership of, or transactions in, the
securities of the Companies, unless earlier revoked in writing.  Each
Reporting Person acknowledges that the Designated Filer and the Authorized
Signatory are not assuming any of the Reporting Person's responsibilities
to comply with any United States federal or state law or with any
regulations promulgated thereto.


     IN WITNESS WHEREOF, the undersigned has caused this Statement
Appointing Designated Filer and Authorized Signatories to be effective
as of September 3, 2002.

	REPORTING PERSONS:

9/3/02		/s/ Thomas J. Fogarty, M.D.
                  ---------------------------
		      Thomas J. Fogarty, M.D.


9/3/02		/s/ Wilfred E. Jaeger
                  ---------------------------
		      Wilfred E. Jaeger


9/3/02		/s/ Mark A. Wan
                  ---------------------------
		      Mark A. Wan


9/3/02		/s/ Barclay Nicholson
                  ---------------------------
		      Barclay Nicholson


9/3/02	      Three Arch Partners, L.P.

	            By:   Three Arch Management, L.P.,
		            Its General Partner


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, General Partner



9/3/02	      Three Arch Associates, L.P.

	            By:   Three Arch Management, L.P.,
		            Its General Partner


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, General Partner


9/3/02	      Three Arch Management, L.P.


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, General Partner


9/3/02	      Three Arch Partners II, L.P.

	            By:   Three Arch Management II, L.L.C.,
		            Its General Partner


	            By:   /s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member


9/3/02	      Three Arch Management II, L.L.C.


	            By:   /s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member


9/3/02	      Three Arch Partners III, L.P.

	            By:   Three Arch Management III, L.L.C.
		            Its General Partner


	            By:   /s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member



9/3/02	      Three Arch Associates III, L.P.

	            By:   Three Arch Management III, L.L.C.
		            Its General Partner


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member


9/3/02	      Three Arch Management III, L.L.C.


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member


9/3/02	      Three Arch Capital, L.P.

	            By:   TAC Management, L.L.C
		            Its General Partner


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member


9/3/02	      TAC Associates, L.P.

	            By:   TAC Management, L.L.C
		            Its General Partner


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member


9/3/02	      TAC Management, L.L.C.


	            By:	/s/ Mark A. Wan
                        ----------------------------
		            Mark A. Wan, Managing Member


                 SCHEDULE A

Three Arch Partners, L.P.
Three Arch Associates, L.P.
Three Arch Management, L.P.
Three Arch Partners II, L.P.
Three Arch Management II, L.L.C.
Three Arch Partners III, L.P.
Three Arch Associates III, L.P.
Three Arch Management III, L.L.C.
Three Arch Capital, L.P.
TAC Associates, L.P.
TAC Management, L.L.C.


                 SCHEDULE B

Thomas J. Fogarty, M.D.
Wilfred E. Jaeger
Mark A. Wan
Barclay Nicholson