Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - Additional Information (Detail)

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Commitments and Contingencies - Additional Information (Detail) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Facilities Operating Leases          
Other Commitments [Line Items]          
Operating lease expense $ 378,000 $ 182,000 $ 1,000,000 $ 387,000  
Laboratory Equipment          
Other Commitments [Line Items]          
Property and equipment, gross 237,000   237,000   $ 171,000
Accumulated amortization $ 100,000   $ 100,000   $ 66,000