Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Contract Assets and Contract Liabilities for Performance Obligations related to Collaboration Agreements (Parenthetical) (Detail)

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Research and Development Agreements - Schedule of Contract Assets and Contract Liabilities for Performance Obligations related to Collaboration Agreements (Parenthetical) (Detail) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Contract With Customer Asset And Liability [Line Items]        
Research and development revenue $ 2,031,000 $ 648,000 $ 3,206,000 $ 2,408,000
Deferred Revenue        
Contract With Customer Asset And Liability [Line Items]        
Research and development revenue     $ 836,000