Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Impact of Adoption on Condensed Consolidated Statement of Cash Flows (Detail)

v3.10.0.1
Research and Development Agreements - Schedule of Impact of Adoption on Condensed Consolidated Statement of Cash Flows (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Revenue Recognition [Line Items]        
Net loss $ 5,244 $ 10,967 $ 23,653 $ 16,225
Changes in operating assets and liabilities:        
Other current assets     (4,313) (57)
Net cash used in operating activities     (23,859) $ (6,354)
ASC 2014-09 | Effect of Adoption of ASC 606        
Revenue Recognition [Line Items]        
Net loss 133   54  
Changes in operating assets and liabilities:        
Other current assets     (54)  
Net cash used in operating activities     0  
ASC 2014-09 | Balance without Adoption of ASC 606        
Revenue Recognition [Line Items]        
Net loss $ 5,111   23,599  
Changes in operating assets and liabilities:        
Other current assets     (4,367)  
Net cash used in operating activities     $ (23,859)