Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Revenue Recognition [Line Items]        
Total research and development revenue $ 3,187 $ 2,031 $ 14,811 $ 3,206
JAPAN        
Revenue Recognition [Line Items]        
Total research and development revenue 2,903 1,914 14,527 3,009
UNITED STATES        
Revenue Recognition [Line Items]        
Total research and development revenue $ 284 $ 117 $ 284 $ 197