Quarterly report pursuant to Section 13 or 15(d)

Stock Based Compensation - Summary of Stock Option Activity Under Equity Incentive Plan (Detail)

v3.23.1
Stock Based Compensation - Summary of Stock Option Activity Under Equity Incentive Plan (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]      
Outstanding Options Number of Shares, Beginning Balance 8,446,463 7,854,473  
Number of Shares, Options granted 2,280,162 2,920,189  
Number of Shares, Options exercised 0 (46,598)  
Number of shares, Options cancelled (522,531) (2,281,601)  
Outstanding Options Number of Shares, Ending Balance 10,204,094 8,446,463 7,854,473
Outstanding Options Number of Shares, Vested and expected to vest, March 31, 2023 10,204,094    
Outstanding Options Number of Shares, Exercisable at March 31, 2023 5,285,428    
Weighted Average Exercise Price, Beginning Balance $ 7.70 $ 10.21  
Weighted Average Exercise Price, Options granted 0.48 2.21  
Weighted Average Exercise Price, Options exercised 0 0.71  
Weighted Average Exercise Price, Options cancelled 5.66 9.44  
Weighted Average Exercise Price, Ending Balance 6.19 $ 7.70 $ 10.21
Weighted Average Exercise Price, Vested and expected to vest, March 31, 2023 6.19    
Weighted Average Exercise Price, Exercisable at March 31, 2023 $ 8.69    
Weighted-Average Remaining Contractual Term, Outstanding 6 years 11 months 23 days 7 years 1 month 2 days 6 years 8 months 19 days
Weighted-Average Remaining Contractual Term, Vested and expected to vest, March 31, 2023 6 years 11 months 23 days    
Weighted-Average Remaining Contractual Term, Exercisable at March 31, 2023 5 years 7 months 20 days    
Aggregate Intrinsic Value, Outstanding $ 0 $ 0 $ 950
Aggregate Intrinsic Value, Vested and expected to vest, March 31, 2023 0    
Aggregate Intrinsic Value, Exercisable at March 31, 2023 $ 0