Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Revenue Recognition [Line Items]    
Total research and development revenue $ 33,627 $ 8,486
JAPAN    
Revenue Recognition [Line Items]    
Total research and development revenue 0 2,586
UNITED STATES    
Revenue Recognition [Line Items]    
Total research and development revenue $ 33,627 $ 5,900