Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Revenue Recognition [Line Items]        
Total research and development revenue $ 4,240 $ 2,379 $ 17,143 $ 20,733
JAPAN        
Revenue Recognition [Line Items]        
Total research and development revenue 0 0 2,586 13,136
UNITED STATES        
Revenue Recognition [Line Items]        
Total research and development revenue $ 4,240 $ 2,379 $ 14,557 $ 7,597