Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Revenue Recognition [Line Items]        
Total research and development revenue $ 2,379 $ 4,298 $ 20,733 $ 12,138
JAPAN        
Revenue Recognition [Line Items]        
Total research and development revenue 0 1,566 13,136 4,962
UNITED STATES        
Revenue Recognition [Line Items]        
Total research and development revenue $ 2,379 $ 2,732 $ 7,597 $ 7,176