Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Research and Development Revenue from Related Party Relates to Revenue from Research and Development Agreements (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenue from Related Party Relates to Revenue from Research and Development Agreements (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Revenue Recognition [Line Items]        
Total research and development revenue, related party $ 15,134 $ 6,040 $ 18,354 $ 7,840
Takeda Development Agreement        
Revenue Recognition [Line Items]        
Total research and development revenue, related party 12,900      
Millennium Pharmaceuticals Inc        
Revenue Recognition [Line Items]        
Total research and development revenue, related party 12,899 3,063 13,136 3,396
Millennium Pharmaceuticals Inc | Takeda Development Agreement        
Revenue Recognition [Line Items]        
Total research and development revenue, related party 12,899 3,028 13,114 3,176
Millennium Pharmaceuticals Inc | Takeda Multi Target Agreement        
Revenue Recognition [Line Items]        
Total research and development revenue, related party $ 0 $ 35 $ 22 $ 220