Quarterly report pursuant to Section 13 or 15(d)

Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail)

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Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Revenue Recognition [Line Items]        
Total research and development revenue $ 15,134 $ 6,040 $ 18,354 $ 7,840
JAPAN        
Revenue Recognition [Line Items]        
Total research and development revenue 12,899 3,063 13,136 3,396
UNITED STATES        
Revenue Recognition [Line Items]        
Total research and development revenue $ 2,235 $ 2,977 $ 5,218 $ 4,444