Quarterly report pursuant to Section 13 or 15(d)

Stock Based Compensation - Stock-Based Compensation Expense (Detail)

v3.5.0.2
Stock Based Compensation - Stock-Based Compensation Expense (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock-based compensation expense $ 802 $ 1,895 $ 1,645 $ 3,316
Research and Development        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock-based compensation expense 306 1,174 624 1,991
General and Administrative        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock-based compensation expense $ 496 $ 721 $ 1,021 $ 1,325