Exclusion Criteria

1. History of another cancer other than basal cell carcinoma or cervical intraepithelial neoplasia (CIN; i.e., cervical cancer in situ).
2. Potential subjects cannot have experienced a significant (CTCAE Grade 3 or 4 with or without neutropenia) infection within 2 weeks of the first dose of MT-3724.
3. Ongoing use of any approved or investigational antineoplastic therapies
4. Systemic corticosteroid therapy at a prednisone dose > 20mg/day (or equivalent) within 14 days prior to study enrollment
5. Potential subjects with pre-existing AEs at screening that are severe or life threatening by CTCAE, v. 4.03 should not be enrolled.
6. Patients with uncontrolled or severe cardiovascular disease, including myocardial infarct or unstable angina within 6 months prior to start of study treatment, New York Heart Association (NYHA) Class II or greater congestive heart failure, serious arrhythmias requiring medication for treatment, clinically significant pericardial disease, or cardiac amyloidosis may not be enrolled.
7. Patients with a known history of drug abuse or any chronic neurologic, psychiatric, endocrine, metabolic, immunologic, hepatic or renal disease (including a history of hemolytic uremic syndrome) that in the opinion of the Investigator would adversely affect study participation.
8. Potential subjects must not have received any vaccines for 28 days prior to administration of their first dose of MT-3724 and should not receive any vaccine during the study or within 28 days after their last dose of MT-3724. The single exception to this exclusion is for the annual influenza (flu) vaccine which can be given up to 14 days prior to first dose.
9. History of hypersensitivity to study drug or to compounds of a similar class, or whose past history suggests an increased potential for an adverse hypersensitivity reaction to MT-3724 should not be enrolled.
10. Patients with known active Hepatitis A or C, HIV or a present history of Hepatitis B
11. Potential subjects who have undergone allogeneic hematopoietic stem cell transplantation.
12. Women who are pregnant or breastfeeding.
13. Potential subjects who have had major surgery within 6 weeks prior to the first dose of study drug or have major surgery planned during the first 12 weeks post MT 3724 exposure

1. Received any amount of anti-CD20 MAb within the following periods before the start of treatment:
   1. Rituximab (Rituxan®/MabThera® or rituximab biosimilar): if administered within 12 to 37 weeks before the start of treatment, then serum rituximab level must be assessed during the screening and confirmed as negative (<500 ng/mL)
   2. Obinutuzumab (Gazyva®/Gazyvaro®): 184 days.
   3. Ofatumumab (Arzerra®): 88 days.
2. Received approved or investigational treatment for NHL (except anti-CD20 MAb and radioimmunoconjugates) within 4 weeks before the start of treatment. Radioimmunoconjugates are excluded within 12 weeks before the start of treatment.
3. Received radiation therapy to target lesions ) within 4 weeks before the start of treatment, unless the lesions exhibited objective progression between radiation therapy and screeninga. Palliative radiation therapy to non-target lesions within 4 weeks before the start of treatment may be permitted at the investigator's discretion.
4. Received systemic immunosuppressive agents (except prescribed corticosteroids at doses ≤20 mg/day prednisone equivalent) within 2 weeks before the start of treatment
5. Received any vaccines except injectable flu (inactivated or recombinant) vaccine within 4 weeks before the start of treatment, or likely to require any vaccines except injectable flu vaccine at any time from the start of treatment until 28 days after the last dose of MT-3724.
6. Received allogeneic stem cell transplant.
7. Current evidence of CTCAE Grade ≥2 (significant) 1 toxicity before the start of treatment, except for hair loss and those significant toxicities permitted in other eligibility criteria. Subjects with significant permitted in other eligibility criteria. Subjects with significant
8. History or current evidence of significant infection, systemic infection or wound within 2 weeks before the start of treatment.a. Subjects with significant infection that has stabilized or improved with oral antibiotics before the start of treatment may be eligible at the investigator's discretion.
9. Known or suspected hypersensitivity to the study drug or excipients contained in the study drug formulation.
10. Current evidence of hypersensitivity or other underlying illness requiring systemic corticosteroids at doses >20 mg/day prednisone equivalent
11. Patients with known active Hepatitis C, HIV or a present history of Hepatitis B
12. Current evidence of incomplete recovery from surgery or radiotherapy at screening, or planned surgery or radiotherapy from the start of treatment until the short term follow-up visit, except minor elective surgery or palliative radiation therapy to non-target lesions deemed acceptable by the investigator.
13. History of cardiovascular, renal, hepatic or any other disease within ≤3 months before the start of treatment
14. History of another primary malignancy within the past 3 years (except for ductal breast cancer in situ, non-melanoma skin cancer, prostate cancer not requiring treatment, and cervical carcinoma in situ) that required systemic drug therapy or radiotherapy.
15. Current evidence of new or growing brain or spinal metastases during screening.
16. Women who are pregnant or breastfeeding.
17. History of non-adherence to the schedule of procedures or medication use