Engineering the Next Generation of Therapeutics

Molecular Templates is a clinical-stage biopharmaceutical company focused on the discovery and development of the next generation of immunotoxins called engineered toxin bodies (ETBs) which are a novel class of therapeutics with unique biology and a differentiated mechanism of action. ETBs are targeted, are designed to induce their own internalization, even against non-internalizing receptors, and destroy tumor cells that are resistant to other modalities. ETBs have been well-tolerated in the clinic to date and show predictable pharmacokinetic and pharmacodynamic effects.

About Us

A New Modality Against Validated Targets

At Molecular Templates, we are developing a pipeline of ETBs that we believe will provide meaningful benefit to patients. ETBs targeting some of the most important receptors in cancer are currently in clinical trials.

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Our Clinical Candidates

MT-6402: 3rd-Gen ETB Targeting PD-L1

MT-6402 targets solid tumors that express PD-L1.

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MT-0169: 2nd-Gen ETB Targeting CD38

MT-0169 targets CD38 for multiple myeloma.

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